Zinc finger protein AEBP2 (AEBP2)
Homo sapiens — UniProt Q6ZN18
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein AEBP2 (AEBP2) is a protein from Homo sapiens identified by UniProt accession Q6ZN18, 517 residues long. MolForge cross-references it against 0 known binders and 72 disease associations.
- UniProt accession: Q6ZN18; gene symbol AEBP2.
- Organism: Homo sapiens.
- Length: 517 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, FEV/FVC ratio and PHF-tau measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein AEBP2 |
|---|---|
| UniProt accession | Q6ZN18 |
| Gene | AEBP2 |
| Organism | Homo sapiens |
| Length | 517 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (72)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.45
- FEV/FVC ratio · score 0.33
- PHF-tau measurement · score 0.29
- systolic blood pressure · score 0.28
- diet measurement · score 0.26
- diastolic blood pressure · score 0.26
- breast adenocarcinoma · score 0.24
- neurofibrillary tangles measurement · score 0.23
- chronic mountain sickness · score 0.23
- Facial wrinkling · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZN18-F1 | alphafold | PREDICTED | 61.84 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZN18.
Amino-acid sequence (517 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AEBP2?
The strongest Open Targets associations for AEBP2 are neurodegenerative disease, FEV/FVC ratio, PHF-tau measurement, systolic blood pressure and diet measurement.
How long is the AEBP2 protein?
The Homo sapiens AEBP2 protein (UniProt Q6ZN18) is 517 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZN18 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZN18 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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