Zinc finger protein basonuclin-2 (BNC2)
Homo sapiens — UniProt Q6ZN30
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein basonuclin-2 (BNC2) is a protein from Homo sapiens identified by UniProt accession Q6ZN30, 1099 residues long. MolForge cross-references it against 0 known binders and 210 disease associations.
- UniProt accession: Q6ZN30; gene symbol BNC2.
- Organism: Homo sapiens.
- Length: 1099 amino acids.
- Top disease associations (Open Targets): fetal lower urinary tract obstruction, posterior urethral valve and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein basonuclin-2 |
|---|---|
| UniProt accession | Q6ZN30 |
| Gene | BNC2 |
| Organism | Homo sapiens |
| Length | 1099 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (210)
Diseases linked to this target (Open Targets).
- fetal lower urinary tract obstruction · score 0.64
- posterior urethral valve · score 0.62
- body height · score 0.51
- heel bone mineral density · score 0.51
- lean body mass · score 0.50
- hair color · score 0.50
- body mass index · score 0.50
- eosinophil count · score 0.50
- body fat percentage · score 0.50
- reticulocyte count · score 0.49
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZN30-F1 | alphafold | PREDICTED | 53.50 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZN30.
Amino-acid sequence (1099 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BNC2?
The strongest Open Targets associations for BNC2 are fetal lower urinary tract obstruction, posterior urethral valve, body height, heel bone mineral density and lean body mass.
How long is the BNC2 protein?
The Homo sapiens BNC2 protein (UniProt Q6ZN30) is 1099 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZN30 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZN30 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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