ETS translocation variant 3-like protein (ETV3L)
Homo sapiens — UniProt Q6ZN32
Data last refreshed: (UniProt release unknown)
Key facts
ETS translocation variant 3-like protein (ETV3L) is a protein from Homo sapiens identified by UniProt accession Q6ZN32, 361 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: Q6ZN32; gene symbol ETV3L.
- Organism: Homo sapiens.
- Length: 361 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, cortical thickness and monocyte percentage of leukocytes.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ETS translocation variant 3-like protein |
|---|---|
| UniProt accession | Q6ZN32 |
| Gene | ETV3L |
| Organism | Homo sapiens |
| Length | 361 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.48
- cortical thickness · score 0.09
- monocyte percentage of leukocytes · score 0.07
- mean corpuscular volume · score 0.04
- neutrophil count · score 0.04
- psoriasis · score 0.02
- brain measurement · score 0.02
- neuroimaging measurement · score 0.02
- Cowden syndrome 1 · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZN32-F1 | alphafold | PREDICTED | 55.22 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZN32.
Amino-acid sequence (361 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ETV3L?
The strongest Open Targets associations for ETV3L are neurodegenerative disease, cortical thickness, monocyte percentage of leukocytes, mean corpuscular volume and neutrophil count.
How long is the ETV3L protein?
The Homo sapiens ETV3L protein (UniProt Q6ZN32) is 361 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZN32 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZN32 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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