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Zinc finger protein 574 (ZNF574)

Homo sapiens — UniProt Q6ZN55

Gene: ZNF574Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Zinc finger protein 574 (ZNF574) is a protein from Homo sapiens identified by UniProt accession Q6ZN55, 896 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.

  • UniProt accession: Q6ZN55; gene symbol ZNF574.
  • Organism: Homo sapiens.
  • Length: 896 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, hepatocellular carcinoma and chronotype measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameZinc finger protein 574
UniProt accessionQ6ZN55
GeneZNF574
OrganismHomo sapiens
Length896 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (16)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.52
  • hepatocellular carcinoma · score 0.15
  • chronotype measurement · score 0.04
  • eosinophil count · score 0.04
  • neuroimaging measurement · score 0.04
  • brain volume measurement · score 0.04
  • sitting height measurement · score 0.03
  • alcohol consumption measurement · score 0.03
  • diet measurement · score 0.03
  • pachyonychia congenita · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6ZN55-F1alphafoldPREDICTED62.01—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZN55.

Amino-acid sequence (896 residues)

MTEESEETVL YIEHRYVCSE CNQLYGSLEE VLMHQNSHVP QQHFELVGVA DPGVTVATDT ASGTGLYQTL VQESQYQCLE CGQLLMSPSQ LLEHQELHLK MMAPQEAVPA EPSPKAPPLS SSTIHYECVD CKALFASQEL WLNHRQTHLR ATPTKAPAPV VLGSPVVLGP PVGQARVAVE HSYRKAEEGG EGATVPSAAA TTTEVVTEVE LLLYKCSECS QLFQLPADFL EHQATHFPAP VPESQEPALQ QEVQASSPAE VPVSQPDPLP ASDHSYELRN GEAIGRDRRG RRARRNNSGE AGGAATQELF CSACDQLFLS PHQLQQHLRS HREGVFKCPL CSRVFPSPSS LDQHLGDHSS ESHFLCVDCG LAFGTEALLL AHRRAHTPNP LHSCPCGKTF VNLTKFLYHR RTHGVGGVPL PTTPVPPEEP VIGFPEPAPA ETGEPEAPEP PVSEETSAGP AAPGTYRCLL CSREFGKALQ LTRHQRFVHR LERRHKCSIC GKMFKKKSHV RNHLRTHTGE RPFPCPDCSK PFNSPANLAR HRLTHTGERP YRCGDCGKAF TQSSTLRQHR LVHAQHFPYR CQECGVRFHR PYRLLMHRYH HTGEYPYKCR ECPRSFLLRR LLEVHQLVVH AGRQPHRCPS CGAAFPSSLR LREHRCAAAA AQAPRRFECG TCGKKVGSAA RLQAHEAAHA AAGPGEVLAK EPPAPRAPRA TRAPVASPAA LGSTATASPA APARRRGLEC SECKKLFSTE TSLQVHRRIH TGERPYPCPD CGKAFRQSTH LKDHRRLHTG ERPFACEVCG KAFAISMRLA EHRRIHTGER PYSCPDCGKS YRSFSNLWKH RKTHQQQHQA AVRQQLAEAE AAVGLAVMET AVEALPLVEA IEIYPLAEAE GVQISG

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZNF574?

The strongest Open Targets associations for ZNF574 are neurodegenerative disease, hepatocellular carcinoma, chronotype measurement, eosinophil count and neuroimaging measurement.

How long is the ZNF574 protein?

The Homo sapiens ZNF574 protein (UniProt Q6ZN55) is 896 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6ZN55
GeneZNF574
OrganismHomo sapiens
Length896
Binders0
Diseases16
View on UniProt