Zinc finger protein ZFP2 (ZFP2)
Homo sapiens — UniProt Q6ZN57
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein ZFP2 (ZFP2) is a protein from Homo sapiens identified by UniProt accession Q6ZN57, 461 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.
- UniProt accession: Q6ZN57; gene symbol ZFP2.
- Organism: Homo sapiens.
- Length: 461 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, refractive error and Abnormality of refraction.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein ZFP2 |
|---|---|
| UniProt accession | Q6ZN57 |
| Gene | ZFP2 |
| Organism | Homo sapiens |
| Length | 461 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (10)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- refractive error · score 0.18
- Abnormality of refraction · score 0.16
- pancreatic adenocarcinoma · score 0.14
- metabolic syndrome · score 0.01
- psoriasis · score 0.01
- metopic craniosynostosis · score 0.00
- Miyoshi myopathy · score 0.00
- cardiovascular disease · score 0.00
- Sepsis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZN57-F1 | alphafold | PREDICTED | 79.75 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZN57.
Amino-acid sequence (461 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZFP2?
The strongest Open Targets associations for ZFP2 are neurodegenerative disease, refractive error, Abnormality of refraction, pancreatic adenocarcinoma and metabolic syndrome.
How long is the ZFP2 protein?
The Homo sapiens ZFP2 protein (UniProt Q6ZN57) is 461 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZN57 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZN57 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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