Coiled-coil domain-containing protein 81 (CCDC81)
Homo sapiens — UniProt Q6ZN84
Data last refreshed: (UniProt release unknown)
Key facts
Coiled-coil domain-containing protein 81 (CCDC81) is a protein from Homo sapiens identified by UniProt accession Q6ZN84, 652 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q6ZN84; gene symbol CCDC81.
- Organism: Homo sapiens.
- Length: 652 amino acids.
- Top disease associations (Open Targets): metabolite measurement, mean reticulocyte volume and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coiled-coil domain-containing protein 81 |
|---|---|
| UniProt accession | Q6ZN84 |
| Gene | CCDC81 |
| Organism | Homo sapiens |
| Length | 652 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- metabolite measurement · score 0.12
- mean reticulocyte volume · score 0.04
- mean corpuscular volume · score 0.03
- gut microbiome measurement · score 0.03
- mean platelet volume · score 0.03
- serum albumin measurement · score 0.03
- adolescent idiopathic scoliosis · score 0.03
- insulin like growth factor measurement · score 0.02
- ependymoma · score 0.02
- cystatin C measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZN84-F1 | alphafold | PREDICTED | 70.53 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZN84.
Amino-acid sequence (652 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCDC81?
The strongest Open Targets associations for CCDC81 are metabolite measurement, mean reticulocyte volume, mean corpuscular volume, gut microbiome measurement and mean platelet volume.
How long is the CCDC81 protein?
The Homo sapiens CCDC81 protein (UniProt Q6ZN84) is 652 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZN84 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZN84 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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