Alkylglycerol monooxygenase (AGMO)
Homo sapiens — UniProt Q6ZNB7
Data last refreshed: (UniProt release unknown)
Key facts
Alkylglycerol monooxygenase (AGMO) is a protein from Homo sapiens identified by UniProt accession Q6ZNB7, 445 residues long. MolForge cross-references it against 0 known binders and 67 disease associations.
- UniProt accession: Q6ZNB7; gene symbol AGMO.
- Organism: Homo sapiens.
- Length: 445 amino acids.
- Top disease associations (Open Targets): vital capacity, heel bone mineral density and neurofibrillary tangles measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Alkylglycerol monooxygenase |
|---|---|
| UniProt accession | Q6ZNB7 |
| Gene | AGMO |
| Organism | Homo sapiens |
| Length | 445 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (67)
Diseases linked to this target (Open Targets).
- vital capacity · score 0.45
- heel bone mineral density · score 0.42
- neurofibrillary tangles measurement · score 0.37
- brain measurement · score 0.34
- forced expiratory volume · score 0.32
- brain volume measurement · score 0.31
- type 2 diabetes mellitus · score 0.31
- PHF-tau measurement · score 0.30
- spinal stenosis · score 0.29
- neuroimaging measurement · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZNB7-F1 | alphafold | PREDICTED | 93.84 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZNB7.
Amino-acid sequence (445 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AGMO?
The strongest Open Targets associations for AGMO are vital capacity, heel bone mineral density, neurofibrillary tangles measurement, brain measurement and forced expiratory volume.
How long is the AGMO protein?
The Homo sapiens AGMO protein (UniProt Q6ZNB7) is 445 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZNB7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZNB7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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