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Zinc finger protein 620 (ZNF620)

Homo sapiens — UniProt Q6ZNG0

Gene: ZNF620Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Zinc finger protein 620 (ZNF620) is a protein from Homo sapiens identified by UniProt accession Q6ZNG0, 422 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.

  • UniProt accession: Q6ZNG0; gene symbol ZNF620.
  • Organism: Homo sapiens.
  • Length: 422 amino acids.
  • Top disease associations (Open Targets): colorectal cancer, eosinophil percentage of leukocytes and arterial stiffness measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameZinc finger protein 620
UniProt accessionQ6ZNG0
GeneZNF620
OrganismHomo sapiens
Length422 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (14)

Diseases linked to this target (Open Targets).

  • colorectal cancer · score 0.15
  • eosinophil percentage of leukocytes · score 0.13
  • arterial stiffness measurement · score 0.11
  • colorectal adenoma · score 0.10
  • blood protein measurement · score 0.10
  • polyp of colon · score 0.09
  • renal cell carcinoma · score 0.07
  • eosinophil count · score 0.06
  • PHF-tau measurement · score 0.06
  • heel bone mineral density · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6ZNG0-F1alphafoldPREDICTED67.04—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZNG0.

Amino-acid sequence (422 residues)

MFQTAWRQEP VTFEDVAVYF TQNEWASLDS VQRALYREVM LENYANVASL AFPFTTPVLV SQLEQGELPW GLDPWEPMGR EALRGICPGD EARTEKEGLT PKDHVSKETE SFRLMVGGLP GNVSQHLDFG SSLEQPQGHW IIKTKSKRRH FTDTSARHHE AYEVKNGEKF EKLGKNISVS TQLTTNQTNP SGQISYECGQ CGRYFIQMAD FHRHEKCHTG EKSFECKECG KYFRYNSLLI RHQIIHTGKK PFKCKECGKG LSSDTALIQH QRIHTGEKPY ECKECGKAFS SSSVFLQHQR FHTGEKLYEC NECWKTFSCS SSFTVHQRMH TGEKPYECKE CGKRLSSNTA LTQHQRIHTG EKPFECKECG KAFNQKITLI QHQRVHTGEK PYECKVCGKT FSWCGRFILH QKLHTQKTPV QA

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZNF620?

The strongest Open Targets associations for ZNF620 are colorectal cancer, eosinophil percentage of leukocytes, arterial stiffness measurement, colorectal adenoma and blood protein measurement.

How long is the ZNF620 protein?

The Homo sapiens ZNF620 protein (UniProt Q6ZNG0) is 422 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6ZNG0
GeneZNF620
OrganismHomo sapiens
Length422
Binders0
Diseases14
View on UniProt