Homeobox protein DBX2 (DBX2)
Homo sapiens — UniProt Q6ZNG2
Data last refreshed: (UniProt release unknown)
Key facts
Homeobox protein DBX2 (DBX2) is a protein from Homo sapiens identified by UniProt accession Q6ZNG2, 339 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.
- UniProt accession: Q6ZNG2; gene symbol DBX2.
- Organism: Homo sapiens.
- Length: 339 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, hepatocellular carcinoma and Gorham-Stout disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Homeobox protein DBX2 |
|---|---|
| UniProt accession | Q6ZNG2 |
| Gene | DBX2 |
| Organism | Homo sapiens |
| Length | 339 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- hepatocellular carcinoma · score 0.08
- Gorham-Stout disease · score 0.07
- neoplasm · score 0.05
- melorheostosis · score 0.05
- glioblastoma multiforme · score 0.04
- psoriasis · score 0.02
- Down syndrome · score 0.01
- glioblastoma · score 0.01
- Intellectual disability · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZNG2-F1 | alphafold | PREDICTED | 57.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZNG2.
Amino-acid sequence (339 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DBX2?
The strongest Open Targets associations for DBX2 are neurodegenerative disease, hepatocellular carcinoma, Gorham-Stout disease, neoplasm and melorheostosis.
How long is the DBX2 protein?
The Homo sapiens DBX2 protein (UniProt Q6ZNG2) is 339 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZNG2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZNG2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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