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Probable beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7 (GCNT7)

Homo sapiens — UniProt Q6ZNI0

Gene: GCNT7Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Probable beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7 (GCNT7) is a protein from Homo sapiens identified by UniProt accession Q6ZNI0, 430 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.

  • UniProt accession: Q6ZNI0; gene symbol GCNT7.
  • Organism: Homo sapiens.
  • Length: 430 amino acids.
  • Top disease associations (Open Targets): reticulocyte count, systolic blood pressure and smoking status measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProbable beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7
UniProt accessionQ6ZNI0
GeneGCNT7
OrganismHomo sapiens
Length430 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (24)

Diseases linked to this target (Open Targets).

  • reticulocyte count · score 0.09
  • systolic blood pressure · score 0.08
  • smoking status measurement · score 0.08
  • hair color · score 0.07
  • hair shape measurement · score 0.07
  • reticulocyte measurement · score 0.07
  • balding measurement · score 0.06
  • protein measurement · score 0.06
  • alopecia · score 0.06
  • Abnormality of refraction · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6ZNI0-F1alphafoldPREDICTED84.40—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZNI0.

Amino-acid sequence (430 residues)

MSQLRATKSG LVVRAVICIF IFLYLRNPTP AESEEEPAQP EVVECGFYPD ELCSALFEGK GAAPQIAKFC KTPHKSEIHA HLHTPGNCSR ISRGLHFITR PLSAEEGDFS LAYIITIHKE LAMFVQLLRA IYVPQNVYCI HVDEKAPMKY KTAVQTLVNC FENVFISSKT EKVAYAGFTR LQADINCMKV LVHSKFQWNY VINLCGQDFP IKTNREIIHY IRSKWSDKNI TPGVIQPLHI KSKTSQSHLE FVPKGSIYAP PNNRFKDKPP HNLTIYFGSA YYVLTRKFVE FILTDIHAKD MLQWSKDIRS PEQHYWVTLN RLKDAPGATP NAGWEGNVRA IKRKSEEGNV HDGCKGRYVE DICVYGPGDL PWLIQSPSLF ANKFEPSTDP LVVTCLERRH RLQVLRQAEV PIEPHWHFQQ QSHFNMRLNR

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with GCNT7?

The strongest Open Targets associations for GCNT7 are reticulocyte count, systolic blood pressure, smoking status measurement, hair color and hair shape measurement.

How long is the GCNT7 protein?

The Homo sapiens GCNT7 protein (UniProt Q6ZNI0) is 430 amino acids long.

Browse: Targets: G · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6ZNI0
GeneGCNT7
OrganismHomo sapiens
Length430
Binders0
Diseases24
View on UniProt