Leucine-rich repeat-containing protein 69 (LRRC69)
Homo sapiens — UniProt Q6ZNQ3
Data last refreshed: (UniProt release unknown)
Key facts
Leucine-rich repeat-containing protein 69 (LRRC69) is a protein from Homo sapiens identified by UniProt accession Q6ZNQ3, 347 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.
- UniProt accession: Q6ZNQ3; gene symbol LRRC69.
- Organism: Homo sapiens.
- Length: 347 amino acids.
- Top disease associations (Open Targets): appendicular lean mass, pulse pressure measurement and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Leucine-rich repeat-containing protein 69 |
|---|---|
| UniProt accession | Q6ZNQ3 |
| Gene | LRRC69 |
| Organism | Homo sapiens |
| Length | 347 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (15)
Diseases linked to this target (Open Targets).
- appendicular lean mass · score 0.34
- pulse pressure measurement · score 0.33
- body height · score 0.32
- neurodegenerative disease · score 0.30
- sitting height measurement · score 0.19
- cortical surface area measurement · score 0.18
- body fat percentage · score 0.10
- type 1 diabetes mellitus · score 0.07
- wellbeing measurement · score 0.03
- depressive symptom measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZNQ3-F1 | alphafold | PREDICTED | 91.65 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZNQ3.
Amino-acid sequence (347 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LRRC69?
The strongest Open Targets associations for LRRC69 are appendicular lean mass, pulse pressure measurement, body height, neurodegenerative disease and sitting height measurement.
How long is the LRRC69 protein?
The Homo sapiens LRRC69 protein (UniProt Q6ZNQ3) is 347 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZNQ3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZNQ3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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