GDP-D-glucose phosphorylase 1 (GDPGP1)
Homo sapiens — UniProt Q6ZNW5
Data last refreshed: (UniProt release unknown)
Key facts
GDP-D-glucose phosphorylase 1 (GDPGP1) is a protein from Homo sapiens identified by UniProt accession Q6ZNW5, 385 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q6ZNW5; gene symbol GDPGP1.
- Organism: Homo sapiens.
- Length: 385 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, serum gamma-glutamyl transferase measurement and alkaline phosphatase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | GDP-D-glucose phosphorylase 1 |
|---|---|
| UniProt accession | Q6ZNW5 |
| Gene | GDPGP1 |
| Organism | Homo sapiens |
| Length | 385 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- serum gamma-glutamyl transferase measurement · score 0.14
- alkaline phosphatase measurement · score 0.07
- polyp of colon · score 0.06
- metabolite measurement · score 0.04
- hair color · score 0.04
- acne · score 0.03
- frontal fibrosing alopecia · score 0.02
- tauopathy · score 0.01
- infect · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZNW5-F1 | alphafold | PREDICTED | 91.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZNW5.
Amino-acid sequence (385 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GDPGP1?
The strongest Open Targets associations for GDPGP1 are neurodegenerative disease, serum gamma-glutamyl transferase measurement, alkaline phosphatase measurement, polyp of colon and metabolite measurement.
How long is the GDPGP1 protein?
The Homo sapiens GDPGP1 protein (UniProt Q6ZNW5) is 385 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZNW5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZNW5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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