Shieldin complex subunit 3 (SHLD3)
Homo sapiens — UniProt Q6ZNX1
Data last refreshed: (UniProt release unknown)
Key facts
Shieldin complex subunit 3 (SHLD3) is a protein from Homo sapiens identified by UniProt accession Q6ZNX1, 250 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.
- UniProt accession: Q6ZNX1; gene symbol SHLD3.
- Organism: Homo sapiens.
- Length: 250 amino acids.
- Top disease associations (Open Targets): reticulocyte count, neuroimaging measurement and brain volume measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Shieldin complex subunit 3 |
|---|---|
| UniProt accession | Q6ZNX1 |
| Gene | SHLD3 |
| Organism | Homo sapiens |
| Length | 250 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.15
- neuroimaging measurement · score 0.12
- brain volume measurement · score 0.12
- thalamus volume · score 0.11
- brain measurement · score 0.11
- reticulocyte measurement · score 0.10
- refractive error measurement · score 0.08
- DNA methylation · score 0.06
- feeling tense measurement · score 0.05
- body height · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZNX1-F1 | alphafold | PREDICTED | 78.53 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZNX1.
Amino-acid sequence (250 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SHLD3?
The strongest Open Targets associations for SHLD3 are reticulocyte count, neuroimaging measurement, brain volume measurement, thalamus volume and brain measurement.
How long is the SHLD3 protein?
The Homo sapiens SHLD3 protein (UniProt Q6ZNX1) is 250 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZNX1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZNX1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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