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Solute carrier organic anion transporter family member 4C1 (SLCO4C1)

Homo sapiens — UniProt Q6ZQN7

Gene: SLCO4C1Homo sapiensSwissProt reviewedTransporter

Data last refreshed: (UniProt release unknown)

Key facts

Solute carrier organic anion transporter family member 4C1 (SLCO4C1) is a protein from Homo sapiens identified by UniProt accession Q6ZQN7, 724 residues long. MolForge cross-references it against 0 known binders and 76 disease associations.

  • UniProt accession: Q6ZQN7; gene symbol SLCO4C1.
  • Organism: Homo sapiens.
  • Length: 724 amino acids.
  • Target class: Transporter.
  • Top disease associations (Open Targets): diastolic blood pressure, BMI-adjusted waist-hip ratio and neurodegenerative disease.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameSolute carrier organic anion transporter family member 4C1
UniProt accessionQ6ZQN7
GeneSLCO4C1
OrganismHomo sapiens
Length724 residues
Molecular weight—
EC numbers—
Target classTransporter (inferred from UniProt keywords / EC)
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (76)

Diseases linked to this target (Open Targets).

  • diastolic blood pressure · score 0.38
  • BMI-adjusted waist-hip ratio · score 0.35
  • neurodegenerative disease · score 0.33
  • allergic rhinitis · score 0.32
  • atopic eczema · score 0.32
  • cutaneous melanoma · score 0.22
  • body height · score 0.21
  • mean arterial pressure · score 0.20
  • cytokine measurement · score 0.18
  • cognitive function measurement · score 0.16

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6ZQN7-F1alphafoldPREDICTED78.62—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZQN7.

Amino-acid sequence (724 residues)

MKSAKGIENL AFVPSSPDIL RRLSASPSQI EVSALSSDPQ RENSQPQELQ KPQEPQKSPE PSLPSAPPNV SEEKLRSLSL SEFEEGSYGW RNFHPQCLQR CNTPGGFLLH YCLLAVTQGI VVNGLVNISI STVEKRYEMK SSLTGLISSS YDISFCLLSL FVSFFGERGH KPRWLAFAAF MIGLGALVFS LPQFFSGEYK LGSLFEDTCV TTRNSTSCTS STSSLSNYLY VFILGQLLLG AGGTPLYTLG TAFLDDSVPT HKSSLYIGTG YAMSILGPAI GYVLGGQLLT IYIDVAMGES TDVTEDDPRW LGAWWIGFLL SWIFAWSLII PFSCFPKHLP GTAEIQAGKT SQAHQSNSNA DVKFGKSIKD FPAALKNLMK NAVFMCLVLS TSSEALITTG FATFLPKFIE NQFGLTSSFA ATLGGAVLIP GAALGQILGG FLVSKFRMTC KNTMKFALFT SGVALTLSFV FMYAKCENEP FAGVSESYNG TGELGNLIAP CNANCNCSRS YYYPVCGDGV QYFSPCFAGC SNPVAHRKPK VYYNCSCIER KTEITSTAET FGFEAKAGKC ETHCAKLPIF LCIFFIVIIF TFMAGTPITV SILRCVNHRQ RSLALGIQFM VLRLLGTIPG PIIFGFTIDS TCILWDINDC GIKGACWIYD NIKMAHMLVA ISVTCKVITM FFNGFAIFLY KPPPSATDVS FHKENAVVTN VLAEQDLNKI VKEG

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SLCO4C1?

The strongest Open Targets associations for SLCO4C1 are diastolic blood pressure, BMI-adjusted waist-hip ratio, neurodegenerative disease, allergic rhinitis and atopic eczema.

How long is the SLCO4C1 protein?

The Homo sapiens SLCO4C1 protein (UniProt Q6ZQN7) is 724 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6ZQN7
GeneSLCO4C1
OrganismHomo sapiens
Length724
Binders0
Diseases76
View on UniProt