Spermatogenesis-associated protein 31D1 (SPATA31D1)
Homo sapiens — UniProt Q6ZQQ2
Data last refreshed: (UniProt release unknown)
Key facts
Spermatogenesis-associated protein 31D1 (SPATA31D1) is a protein from Homo sapiens identified by UniProt accession Q6ZQQ2, 1576 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.
- UniProt accession: Q6ZQQ2; gene symbol SPATA31D1.
- Organism: Homo sapiens.
- Length: 1576 amino acids.
- Top disease associations (Open Targets): schizophrenia, FEV/FVC ratio and spondin-1 measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Spermatogenesis-associated protein 31D1 |
|---|---|
| UniProt accession | Q6ZQQ2 |
| Gene | SPATA31D1 |
| Organism | Homo sapiens |
| Length | 1576 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (35)
Diseases linked to this target (Open Targets).
- schizophrenia · score 0.42
- FEV/FVC ratio · score 0.41
- spondin-1 measurement · score 0.29
- migraine disorder · score 0.26
- body height · score 0.14
- autism spectrum disorder · score 0.14
- rheumatoid arthritis · score 0.11
- visual perception measurement · score 0.08
- acroleukopathy, symmetric · score 0.07
- familial generalized lentiginosis · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZQQ2-F1 | alphafold | PREDICTED | 39.76 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZQQ2.
Amino-acid sequence (1576 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPATA31D1?
The strongest Open Targets associations for SPATA31D1 are schizophrenia, FEV/FVC ratio, spondin-1 measurement, migraine disorder and body height.
How long is the SPATA31D1 protein?
The Homo sapiens SPATA31D1 protein (UniProt Q6ZQQ2) is 1576 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZQQ2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZQQ2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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