Indoleamine 2,3-dioxygenase 2 (IDO2)
Homo sapiens — UniProt Q6ZQW0
Data last refreshed: (UniProt release unknown)
Key facts
Indoleamine 2,3-dioxygenase 2 (IDO2) is a protein from Homo sapiens identified by UniProt accession Q6ZQW0, 407 residues long. MolForge cross-references it against 0 known binders and 331 disease associations.
- UniProt accession: Q6ZQW0; gene symbol IDO2.
- Organism: Homo sapiens.
- Length: 407 amino acids.
- Top disease associations (Open Targets): blood metabolite measurement, neoplasm and psoriasis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Indoleamine 2,3-dioxygenase 2 |
|---|---|
| UniProt accession | Q6ZQW0 |
| Gene | IDO2 |
| Organism | Homo sapiens |
| Length | 407 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (331)
Diseases linked to this target (Open Targets).
- blood metabolite measurement · score 0.28
- neoplasm · score 0.10
- psoriasis · score 0.08
- experimental autoimmune encephalomyelitis · score 0.08
- non-small cell lung carcinoma · score 0.07
- hepatocellular carcinoma · score 0.06
- diffuse large B-cell lymphoma · score 0.06
- cancer · score 0.06
- long COVID-19 · score 0.05
- dermatitis · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZQW0-F1 | alphafold | PREDICTED | 93.07 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZQW0.
Amino-acid sequence (407 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IDO2?
The strongest Open Targets associations for IDO2 are blood metabolite measurement, neoplasm, psoriasis, experimental autoimmune encephalomyelitis and non-small cell lung carcinoma.
How long is the IDO2 protein?
The Homo sapiens IDO2 protein (UniProt Q6ZQW0) is 407 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZQW0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZQW0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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