Protein LIAT1 (LIAT1)
Homo sapiens — UniProt Q6ZQX7
Data last refreshed: (UniProt release unknown)
Key facts
Protein LIAT1 (LIAT1) is a protein from Homo sapiens identified by UniProt accession Q6ZQX7, 453 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q6ZQX7; gene symbol LIAT1.
- Organism: Homo sapiens.
- Length: 453 amino acids.
- Top disease associations (Open Targets): BMI-adjusted waist circumference, physical activity measurement and benign lipomatous neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein LIAT1 |
|---|---|
| UniProt accession | Q6ZQX7 |
| Gene | LIAT1 |
| Organism | Homo sapiens |
| Length | 453 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist circumference · score 0.08
- physical activity measurement · score 0.07
- benign lipomatous neoplasm · score 0.04
- IGF-1 measurement · score 0.04
- BMI-adjusted hip circumference · score 0.04
- attention deficit hyperactivity disorder · score 0.04
- drug use measurement · score 0.03
- urinary bladder carcinoma · score 0.01
- schizophrenia · score 0.00
- Parkinson disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZQX7-F1 | alphafold | PREDICTED | 46.41 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZQX7.
Amino-acid sequence (453 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LIAT1?
The strongest Open Targets associations for LIAT1 are BMI-adjusted waist circumference, physical activity measurement, benign lipomatous neoplasm, IGF-1 measurement and BMI-adjusted hip circumference.
How long is the LIAT1 protein?
The Homo sapiens LIAT1 protein (UniProt Q6ZQX7) is 453 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZQX7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZQX7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.