Acidic amino acid decarboxylase GADL1 (GADL1)
Homo sapiens — UniProt Q6ZQY3
Data last refreshed: (UniProt release unknown)
Key facts
Acidic amino acid decarboxylase GADL1 (GADL1) is a protein from Homo sapiens identified by UniProt accession Q6ZQY3, 521 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.
- UniProt accession: Q6ZQY3; gene symbol GADL1.
- Organism: Homo sapiens.
- Length: 521 amino acids.
- Top disease associations (Open Targets): blood protein measurement, glomerular filtration rate and neuroinflammatory disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Acidic amino acid decarboxylase GADL1 |
|---|---|
| UniProt accession | Q6ZQY3 |
| Gene | GADL1 |
| Organism | Homo sapiens |
| Length | 521 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (39)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.32
- glomerular filtration rate · score 0.30
- neuroinflammatory disorder · score 0.30
- body height · score 0.28
- neurofibrillary tangles measurement · score 0.28
- serum metabolite measurement · score 0.27
- appendicular lean mass · score 0.25
- blood metabolite measurement · score 0.25
- neurodegenerative disease · score 0.24
- grip strength measurement · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZQY3-F1 | alphafold | PREDICTED | 94.56 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZQY3.
Amino-acid sequence (521 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GADL1?
The strongest Open Targets associations for GADL1 are blood protein measurement, glomerular filtration rate, neuroinflammatory disorder, body height and neurofibrillary tangles measurement.
How long is the GADL1 protein?
The Homo sapiens GADL1 protein (UniProt Q6ZQY3) is 521 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZQY3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZQY3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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