Zinc finger protein 493 (ZNF493)
Homo sapiens — UniProt Q6ZR52
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 493 (ZNF493) is a protein from Homo sapiens identified by UniProt accession Q6ZR52, 646 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.
- UniProt accession: Q6ZR52; gene symbol ZNF493.
- Organism: Homo sapiens.
- Length: 646 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, hypertension and erythrocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 493 |
|---|---|
| UniProt accession | Q6ZR52 |
| Gene | ZNF493 |
| Organism | Homo sapiens |
| Length | 646 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (63)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.41
- hypertension · score 0.28
- erythrocyte count · score 0.13
- Blackfan-Diamond anemia · score 0.05
- mean corpuscular volume · score 0.05
- X-linked severe congenital neutropenia · score 0.04
- neutropenia, severe congenital, 2, autosomal dominant · score 0.04
- thyroid disease · score 0.04
- nonimmune chronic idiopathic neutropenia of adults · score 0.04
- autosomal recessive severe congenital neutropenia due to CSF3R deficiency · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZR52-F1 | alphafold | PREDICTED | 78.48 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZR52.
Amino-acid sequence (646 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF493?
The strongest Open Targets associations for ZNF493 are neurodegenerative disease, hypertension, erythrocyte count, Blackfan-Diamond anemia and mean corpuscular volume.
How long is the ZNF493 protein?
The Homo sapiens ZNF493 protein (UniProt Q6ZR52) is 646 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZR52 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZR52 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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