Cation channel sperm-associated auxiliary subunit gamma (CATSPERG)
Homo sapiens — UniProt Q6ZRH7
Data last refreshed: (UniProt release unknown)
Key facts
Cation channel sperm-associated auxiliary subunit gamma (CATSPERG) is a protein from Homo sapiens identified by UniProt accession Q6ZRH7, 1159 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q6ZRH7; gene symbol CATSPERG.
- Organism: Homo sapiens.
- Length: 1159 amino acids.
- Target class: Ion channel.
- Top disease associations (Open Targets): mean platelet volume, cutaneous melanoma and lung adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cation channel sperm-associated auxiliary subunit gamma |
|---|---|
| UniProt accession | Q6ZRH7 |
| Gene | CATSPERG |
| Organism | Homo sapiens |
| Length | 1159 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Ion channel (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.30
- cutaneous melanoma · score 0.25
- lung adenocarcinoma · score 0.23
- breast adenocarcinoma · score 0.16
- platelet count · score 0.16
- squamous cell lung carcinoma · score 0.15
- glioblastoma multiforme · score 0.15
- head and neck squamous cell carcinoma · score 0.13
- prostate carcinoma · score 0.10
- high density lipoprotein cholesterol measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZRH7-F1 | alphafold | PREDICTED | 83.85 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZRH7.
Amino-acid sequence (1159 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CATSPERG?
The strongest Open Targets associations for CATSPERG are mean platelet volume, cutaneous melanoma, lung adenocarcinoma, breast adenocarcinoma and platelet count.
How long is the CATSPERG protein?
The Homo sapiens CATSPERG protein (UniProt Q6ZRH7) is 1159 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZRH7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZRH7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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