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Coiled-coil domain-containing protein 73 (CCDC73)

Homo sapiens — UniProt Q6ZRK6

Gene: CCDC73Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Coiled-coil domain-containing protein 73 (CCDC73) is a protein from Homo sapiens identified by UniProt accession Q6ZRK6, 1079 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.

  • UniProt accession: Q6ZRK6; gene symbol CCDC73.
  • Organism: Homo sapiens.
  • Length: 1079 amino acids.
  • Top disease associations (Open Targets): platelet count, Inguinal hernia and unipolar depression.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameCoiled-coil domain-containing protein 73
UniProt accessionQ6ZRK6
GeneCCDC73
OrganismHomo sapiens
Length1079 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (29)

Diseases linked to this target (Open Targets).

  • platelet count · score 0.32
  • Inguinal hernia · score 0.28
  • unipolar depression · score 0.20
  • sitting height measurement · score 0.19
  • bipolar disorder · score 0.19
  • substance abuse · score 0.18
  • antisocial behaviour measurement · score 0.18
  • attention deficit hyperactivity disorder · score 0.18
  • cystatin C measurement · score 0.16
  • sex hormone-binding globulin measurement · score 0.15

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6ZRK6-F1alphafoldPREDICTED53.62—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZRK6.

Amino-acid sequence (1079 residues)

MESNFNTESS STFTLQSSSE TLFSIQLLDF KTSLLEALEE LRMRREAEIH YEEQIGKIIV ETQELKWQKE TLQNQKETLA EQHKEAMAVF KKQLQMKMCA LEEEKGKYQL ATEIKEKEIE GLKETLKALQ VSKYSLQKKV SEMEQKVQLH LLAKEDYHKQ LSEIEKYYAT ITGQFGLVKE NHEKLEQNVR EAIQSNKRLS ALNKKQEAEI CSLKKELKKA ASDLIKSKVT CQYKMGEENI NLTIKEQKFQ ELQERLNMEL ELNEKINEEI THIQEEKQDI IISFQHMQQL LRQQIQANTE MEAELKVLKE NNQTLERDNE LQREKVKENE EKFLNLQNEH EKALGTWKRH AEELNGEINK IKNELSSLKE THIKLQEHYN KLCNQKTFEE DKKFQNVPEV NNENSEMSTE KSENTIIQKY NTEQEIREEN MENFCSDTEY REKEEKKEGS FIEEIIIDDL QLFEKSFKNE IDTVVSQDEN QSEISLSKTL SLDKEVISQG QTSNVTDNRK SVTTEIKDKI CLEKDNGCTE FKSPNNHFVV LDTAIETEKI HLERTRGLDV HHTDVNLEVE NNKTSFNSIL NETAHNTYHN NNKDVSENEP FKQFRLLPGT REHALEKEIT NSDQTKADLD SSLDIKKNPV PCQKYSLRNS SNVMLDDKQC KIKQIQLLTK KSECSILLSK QTSDFLQVCN DTLEKSELTV PCDIVIDHHV SYAAFSANSK LLLKNSDKNV HSMSMLVKPN SSPGGKTMCK NMSDMQNSQF NNCLGYLENT NVNISHLHLN NENSHASQAK DVKTAVHMKT CTETEFSNKK NQIDENQVTE ATKNDLFLFV SINERQHTLL NNTEKTESLN DIVSGKMFSE GQLEESHSFH IEPSGDLVNR SGRSTFDLST SDKKTEKTPV YMNFSDPGPW SKVNHIESQT ASSSTPCISL LLKERPLDPS ENKKIISMAL CKNIGVDDVG KDIGPDTTSI NRVADTLNNW SIHPDPKGEP SEEKNAMAKT FYDSSFPTEH VKTKPLISTP LQSHLQAIKT TKNTSGDDDW QSLITNQLNK SENLLSLEND NQPKKRKAEE TLEKNNRLK

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CCDC73?

The strongest Open Targets associations for CCDC73 are platelet count, Inguinal hernia, unipolar depression, sitting height measurement and bipolar disorder.

How long is the CCDC73 protein?

The Homo sapiens CCDC73 protein (UniProt Q6ZRK6) is 1079 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6ZRK6
GeneCCDC73
OrganismHomo sapiens
Length1079
Binders0
Diseases29
View on UniProt