Protein ITPRID1 (ITPRID1)
Homo sapiens — UniProt Q6ZRS4
Data last refreshed: (UniProt release unknown)
Key facts
Protein ITPRID1 (ITPRID1) is a protein from Homo sapiens identified by UniProt accession Q6ZRS4, 1044 residues long. MolForge cross-references it against 0 known binders and 103 disease associations.
- UniProt accession: Q6ZRS4; gene symbol ITPRID1.
- Organism: Homo sapiens.
- Length: 1044 amino acids.
- Top disease associations (Open Targets): carpal tunnel syndrome, psoriasis and metabolite measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein ITPRID1 |
|---|---|
| UniProt accession | Q6ZRS4 |
| Gene | ITPRID1 |
| Organism | Homo sapiens |
| Length | 1044 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (103)
Diseases linked to this target (Open Targets).
- carpal tunnel syndrome · score 0.27
- psoriasis · score 0.23
- metabolite measurement · score 0.08
- Blackfan-Diamond anemia · score 0.07
- X-linked severe congenital neutropenia · score 0.06
- neutropenia, severe congenital, 2, autosomal dominant · score 0.05
- neutropenia, severe congenital, 1, autosomal dominant · score 0.05
- nonimmune chronic idiopathic neutropenia of adults · score 0.05
- myeloperoxidase deficiency · score 0.05
- chronic myeloproliferative disorder · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZRS4-F1 | alphafold | PREDICTED | 46.45 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZRS4.
Amino-acid sequence (1044 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ITPRID1?
The strongest Open Targets associations for ITPRID1 are carpal tunnel syndrome, psoriasis, metabolite measurement, Blackfan-Diamond anemia and X-linked severe congenital neutropenia.
How long is the ITPRID1 protein?
The Homo sapiens ITPRID1 protein (UniProt Q6ZRS4) is 1044 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZRS4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZRS4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.