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C-type lectin domain family 17, member A (CLEC17A)

Homo sapiens — UniProt Q6ZS10

Gene: CLEC17AHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

C-type lectin domain family 17, member A (CLEC17A) is a protein from Homo sapiens identified by UniProt accession Q6ZS10, 378 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.

  • UniProt accession: Q6ZS10; gene symbol CLEC17A.
  • Organism: Homo sapiens.
  • Length: 378 amino acids.
  • Top disease associations (Open Targets): bone density, urate measurement and Hiatus hernia.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameC-type lectin domain family 17, member A
UniProt accessionQ6ZS10
GeneCLEC17A
OrganismHomo sapiens
Length378 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (27)

Diseases linked to this target (Open Targets).

  • bone density · score 0.25
  • urate measurement · score 0.25
  • Hiatus hernia · score 0.15
  • genetic disorder · score 0.12
  • neoplasm · score 0.06
  • metabolite measurement · score 0.04
  • mean corpuscular hemoglobin concentration · score 0.03
  • psoriasis · score 0.01
  • lung adenocarcinoma · score 0.01
  • COVID-19 · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6ZS10-F1alphafoldPREDICTED70.21—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZS10.

Amino-acid sequence (378 residues)

MHNLYSITGY PDPPGTMEEE EEDDDYENST PPYKDLPPKP GTMEEEEEDD DYENSTPPYK DLPPKPGTME EEEEDDDYEN STPPYKDLPP KPGSSAPPRP PRAAKETEKP PLPCKPRNMT GLDLAAVTCP PPQLAVNLEP SPLQPSLAAT PVPWLNQRSG GPGCCQKRWM VYLCLLVVTS LFLGCLGLTV TLIKYQELME ELRMLSFQQM TWRTNMTGMA GLAGLKHDIA RVRADTNQSL VELWGLLDCR RITCPEGWLP FEGKCYYFSP STKSWDEARM FCQENYSHLV IINSFAEHNF VAKAHGSPRV YWLGLNDRAQ EGDWRWLDGS PVTLSFWEPE EPNNIHDEDC ATMNKGGTWN DLSCYKTTYW ICERKCSC

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CLEC17A?

The strongest Open Targets associations for CLEC17A are bone density, urate measurement, Hiatus hernia, genetic disorder and neoplasm.

How long is the CLEC17A protein?

The Homo sapiens CLEC17A protein (UniProt Q6ZS10) is 378 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6ZS10
GeneCLEC17A
OrganismHomo sapiens
Length378
Binders0
Diseases27
View on UniProt