Ras and Rab interactor-like protein (RINL)
Homo sapiens — UniProt Q6ZS11
Data last refreshed: (UniProt release unknown)
Key facts
Ras and Rab interactor-like protein (RINL) is a protein from Homo sapiens identified by UniProt accession Q6ZS11, 566 residues long. MolForge cross-references it against 0 known binders and 114 disease associations.
- UniProt accession: Q6ZS11; gene symbol RINL.
- Organism: Homo sapiens.
- Length: 566 amino acids.
- Top disease associations (Open Targets): platelet crit, Blackfan-Diamond anemia and alpha thalassemia-intellectual disability syndrome type 1.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ras and Rab interactor-like protein |
|---|---|
| UniProt accession | Q6ZS11 |
| Gene | RINL |
| Organism | Homo sapiens |
| Length | 566 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (114)
Diseases linked to this target (Open Targets).
- platelet crit · score 0.17
- Blackfan-Diamond anemia · score 0.09
- alpha thalassemia-intellectual disability syndrome type 1 · score 0.07
- Alpha-thalassemia - intellectual disability syndrome linked to chromosome 16 · score 0.07
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome · score 0.06
- common variable immunodeficiency · score 0.06
- hemolytic anemia due to adenylate kinase deficiency · score 0.06
- hemoglobin C-beta-thalassemia syndrome · score 0.06
- Heinz body anemia · score 0.05
- dominant beta-thalassemia · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZS11-F1 | alphafold | PREDICTED | 66.05 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZS11.
Amino-acid sequence (566 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RINL?
The strongest Open Targets associations for RINL are platelet crit, Blackfan-Diamond anemia, alpha thalassemia-intellectual disability syndrome type 1, Alpha-thalassemia - intellectual disability syndrome linked to chromosome 16 and hereditary persistence of fetal hemoglobin-sickle cell disease syndrome.
How long is the RINL protein?
The Homo sapiens RINL protein (UniProt Q6ZS11) is 566 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZS11 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZS11 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.