Rho family-interacting cell polarization regulator 1 (RIPOR1)
Homo sapiens — UniProt Q6ZS17
Data last refreshed: (UniProt release unknown)
Key facts
Rho family-interacting cell polarization regulator 1 (RIPOR1) is a protein from Homo sapiens identified by UniProt accession Q6ZS17, 1223 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.
- UniProt accession: Q6ZS17; gene symbol RIPOR1.
- Organism: Homo sapiens.
- Length: 1223 amino acids.
- Top disease associations (Open Targets): eosinophil count, eosinophil percentage of leukocytes and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Rho family-interacting cell polarization regulator 1 |
|---|---|
| UniProt accession | Q6ZS17 |
| Gene | RIPOR1 |
| Organism | Homo sapiens |
| Length | 1223 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (47)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.10
- eosinophil percentage of leukocytes · score 0.08
- neoplasm · score 0.07
- mean corpuscular volume · score 0.07
- testosterone measurement · score 0.07
- mean platelet volume · score 0.06
- FEV/FVC ratio · score 0.05
- erythrocyte count · score 0.04
- BMI-adjusted waist-hip ratio · score 0.03
- cancer · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZS17-F1 | alphafold | PREDICTED | 62.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZS17.
Amino-acid sequence (1223 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RIPOR1?
The strongest Open Targets associations for RIPOR1 are eosinophil count, eosinophil percentage of leukocytes, neoplasm, mean corpuscular volume and testosterone measurement.
How long is the RIPOR1 protein?
The Homo sapiens RIPOR1 protein (UniProt Q6ZS17) is 1223 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZS17 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZS17 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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