Glycerol kinase 5 (GK5)
Homo sapiens — UniProt Q6ZS86
Data last refreshed: (UniProt release unknown)
Key facts
Glycerol kinase 5 (GK5) is a protein from Homo sapiens identified by UniProt accession Q6ZS86, 529 residues long. MolForge cross-references it against 0 known binders and 97 disease associations.
- UniProt accession: Q6ZS86; gene symbol GK5.
- Organism: Homo sapiens.
- Length: 529 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, mean corpuscular volume and serum alanine aminotransferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Glycerol kinase 5 |
|---|---|
| UniProt accession | Q6ZS86 |
| Gene | GK5 |
| Organism | Homo sapiens |
| Length | 529 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (97)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.44
- mean corpuscular volume · score 0.26
- serum alanine aminotransferase measurement · score 0.21
- C-reactive protein measurement · score 0.20
- mean corpuscular hemoglobin concentration · score 0.19
- Alopecia-intellectual disability syndrome · score 0.11
- Alopecia universalis · score 0.11
- alopecia, androgenetic, 1 · score 0.10
- central centrifugal cicatricial alopecia · score 0.10
- hypotrichosis simplex · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZS86-F1 | alphafold | PREDICTED | 93.88 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZS86.
Amino-acid sequence (529 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GK5?
The strongest Open Targets associations for GK5 are neurodegenerative disease, mean corpuscular volume, serum alanine aminotransferase measurement, C-reactive protein measurement and mean corpuscular hemoglobin concentration.
How long is the GK5 protein?
The Homo sapiens GK5 protein (UniProt Q6ZS86) is 529 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZS86 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZS86 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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