Zinc finger and BTB domain-containing protein 49 (ZBTB49)
Homo sapiens — UniProt Q6ZSB9
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger and BTB domain-containing protein 49 (ZBTB49) is a protein from Homo sapiens identified by UniProt accession Q6ZSB9, 765 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: Q6ZSB9; gene symbol ZBTB49.
- Organism: Homo sapiens.
- Length: 765 amino acids.
- Top disease associations (Open Targets): DNA methylation, physical activity measurement and cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger and BTB domain-containing protein 49 |
|---|---|
| UniProt accession | Q6ZSB9 |
| Gene | ZBTB49 |
| Organism | Homo sapiens |
| Length | 765 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- DNA methylation · score 0.14
- physical activity measurement · score 0.06
- cancer · score 0.04
- diabetic maculopathy · score 0.03
- visual perception measurement · score 0.03
- protein measurement · score 0.02
- adolescent idiopathic scoliosis · score 0.02
- hair colour measurement · score 0.02
- neoplasm · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZSB9-F1 | alphafold | PREDICTED | 57.18 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZSB9.
Amino-acid sequence (765 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZBTB49?
The strongest Open Targets associations for ZBTB49 are DNA methylation, physical activity measurement, cancer, diabetic maculopathy and visual perception measurement.
How long is the ZBTB49 protein?
The Homo sapiens ZBTB49 protein (UniProt Q6ZSB9) is 765 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZSB9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZSB9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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