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Uncharacterized protein C1orf122 (C1orf122)

Homo sapiens — UniProt Q6ZSJ8

Gene: C1orf122Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Uncharacterized protein C1orf122 (C1orf122) is a protein from Homo sapiens identified by UniProt accession Q6ZSJ8, 110 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.

  • UniProt accession: Q6ZSJ8; gene symbol C1orf122.
  • Organism: Homo sapiens.
  • Length: 110 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, Galloway-Mowat syndrome 10 and lysosomal storage disease.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameUncharacterized protein C1orf122
UniProt accessionQ6ZSJ8
GeneC1orf122
OrganismHomo sapiens
Length110 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (24)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.35
  • Galloway-Mowat syndrome 10 · score 0.33
  • lysosomal storage disease · score 0.18
  • mathematical ability · score 0.12
  • pulse pressure measurement · score 0.11
  • systemic lupus erythematosus · score 0.08
  • vital capacity · score 0.07
  • hypothyroidism · score 0.05
  • platelet component distribution width · score 0.05
  • blood protein measurement · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6ZSJ8-F1alphafoldPREDICTED67.04—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZSJ8.

Amino-acid sequence (110 residues)

MEWGPGSDWS RGEAAGVDRG KAGLGLGGRP PPQPPREERA QQLLDAVEQR QRQLLDTIAA CEEMLRQLGR RRPEPAGGGN VSAKPGAPPQ PAVSARGGFP KDAGDGAAEP

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with C1orf122?

The strongest Open Targets associations for C1orf122 are neurodegenerative disease, Galloway-Mowat syndrome 10, lysosomal storage disease, mathematical ability and pulse pressure measurement.

How long is the C1orf122 protein?

The Homo sapiens C1orf122 protein (UniProt Q6ZSJ8) is 110 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6ZSJ8
GeneC1orf122
OrganismHomo sapiens
Length110
Binders0
Diseases24
View on UniProt