Monocarboxylate transporter 12 (SLC16A12)
Homo sapiens — UniProt Q6ZSM3
Data last refreshed: (UniProt release unknown)
Key facts
Monocarboxylate transporter 12 (SLC16A12) is a protein from Homo sapiens identified by UniProt accession Q6ZSM3, 516 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.
- UniProt accession: Q6ZSM3; gene symbol SLC16A12.
- Organism: Homo sapiens.
- Length: 516 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): juvenile cataract-microcornea-renal glucosuria syndrome, Juvenile cataract - microcornea - renal glucosuria and electrocardiography.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Monocarboxylate transporter 12 |
|---|---|
| UniProt accession | Q6ZSM3 |
| Gene | SLC16A12 |
| Organism | Homo sapiens |
| Length | 516 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (39)
Diseases linked to this target (Open Targets).
- juvenile cataract-microcornea-renal glucosuria syndrome · score 0.62
- Juvenile cataract - microcornea - renal glucosuria · score 0.56
- electrocardiography · score 0.49
- mathematical ability · score 0.40
- body height · score 0.32
- creatinine measurement · score 0.32
- coloboma · score 0.11
- Developmental cataract · score 0.11
- early-onset non-syndromic cataract · score 0.11
- platelet crit · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZSM3-F1 | alphafold | PREDICTED | 80.27 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZSM3.
Amino-acid sequence (516 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC16A12?
The strongest Open Targets associations for SLC16A12 are juvenile cataract-microcornea-renal glucosuria syndrome, Juvenile cataract - microcornea - renal glucosuria, electrocardiography, mathematical ability and body height.
How long is the SLC16A12 protein?
The Homo sapiens SLC16A12 protein (UniProt Q6ZSM3) is 516 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZSM3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZSM3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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