Protein phosphatase 1 regulatory subunit 3F (PPP1R3F)
Homo sapiens — UniProt Q6ZSY5
Data last refreshed: (UniProt release unknown)
Key facts
Protein phosphatase 1 regulatory subunit 3F (PPP1R3F) is a protein from Homo sapiens identified by UniProt accession Q6ZSY5, 799 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q6ZSY5; gene symbol PPP1R3F.
- Organism: Homo sapiens.
- Length: 799 amino acids.
- Top disease associations (Open Targets): Neurodevelopmental disorder, neurodegenerative disease and Intellectual disability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein phosphatase 1 regulatory subunit 3F |
|---|---|
| UniProt accession | Q6ZSY5 |
| Gene | PPP1R3F |
| Organism | Homo sapiens |
| Length | 799 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- Neurodevelopmental disorder · score 0.47
- neurodegenerative disease · score 0.46
- Intellectual disability · score 0.37
- epilepsy · score 0.37
- glioblastoma multiforme · score 0.02
- Global developmental delay · score 0.01
- neoplasm · score 0.01
- Ataxia-telangiectasia · score 0.00
- papillary thyroid carcinoma · score 0.00
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZSY5-F1 | alphafold | PREDICTED | 48.80 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZSY5.
Amino-acid sequence (799 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PPP1R3F?
The strongest Open Targets associations for PPP1R3F are Neurodevelopmental disorder, neurodegenerative disease, Intellectual disability, epilepsy and glioblastoma multiforme.
How long is the PPP1R3F protein?
The Homo sapiens PPP1R3F protein (UniProt Q6ZSY5) is 799 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZSY5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZSY5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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