Teashirt homolog 1 (TSHZ1)
Homo sapiens — UniProt Q6ZSZ6
Data last refreshed: (UniProt release unknown)
Key facts
Teashirt homolog 1 (TSHZ1) is a protein from Homo sapiens identified by UniProt accession Q6ZSZ6, 1077 residues long. MolForge cross-references it against 0 known binders and 135 disease associations.
- UniProt accession: Q6ZSZ6; gene symbol TSHZ1.
- Organism: Homo sapiens.
- Length: 1077 amino acids.
- Top disease associations (Open Targets): Abnormality of the ear, systolic blood pressure and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Teashirt homolog 1 |
|---|---|
| UniProt accession | Q6ZSZ6 |
| Gene | TSHZ1 |
| Organism | Homo sapiens |
| Length | 1077 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (135)
Diseases linked to this target (Open Targets).
- Abnormality of the ear · score 0.57
- systolic blood pressure · score 0.46
- platelet count · score 0.37
- protein measurement · score 0.35
- diastolic blood pressure · score 0.34
- colorectal cancer · score 0.25
- endometrial neoplasm · score 0.25
- lymphocyte count · score 0.24
- prostate carcinoma · score 0.19
- platelet crit · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZSZ6-F1 | alphafold | PREDICTED | 54.04 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZSZ6.
Amino-acid sequence (1077 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TSHZ1?
The strongest Open Targets associations for TSHZ1 are Abnormality of the ear, systolic blood pressure, platelet count, protein measurement and diastolic blood pressure.
How long is the TSHZ1 protein?
The Homo sapiens TSHZ1 protein (UniProt Q6ZSZ6) is 1077 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZSZ6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZSZ6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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