TBC1 domain family member 9 (TBC1D9)
Homo sapiens — UniProt Q6ZT07
Data last refreshed: (UniProt release unknown)
Key facts
TBC1 domain family member 9 (TBC1D9) is a protein from Homo sapiens identified by UniProt accession Q6ZT07, 1266 residues long. MolForge cross-references it against 0 known binders and 50 disease associations.
- UniProt accession: Q6ZT07; gene symbol TBC1D9.
- Organism: Homo sapiens.
- Length: 1266 amino acids.
- Top disease associations (Open Targets): platelet count, platelet crit and attention deficit hyperactivity disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | TBC1 domain family member 9 |
|---|---|
| UniProt accession | Q6ZT07 |
| Gene | TBC1D9 |
| Organism | Homo sapiens |
| Length | 1266 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (50)
Diseases linked to this target (Open Targets).
- platelet count · score 0.18
- platelet crit · score 0.14
- attention deficit hyperactivity disorder · score 0.11
- triple-negative breast cancer · score 0.08
- PHF-tau measurement · score 0.08
- neoplasm · score 0.08
- breast cancer · score 0.08
- BMI-adjusted hip circumference · score 0.06
- juvenile idiopathic arthritis · score 0.03
- prostate carcinoma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZT07-F1 | alphafold | PREDICTED | 72.44 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZT07.
Amino-acid sequence (1266 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TBC1D9?
The strongest Open Targets associations for TBC1D9 are platelet count, platelet crit, attention deficit hyperactivity disorder, triple-negative breast cancer and PHF-tau measurement.
How long is the TBC1D9 protein?
The Homo sapiens TBC1D9 protein (UniProt Q6ZT07) is 1266 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZT07 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZT07 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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