Protein FAM43B (FAM43B)
Homo sapiens — UniProt Q6ZT52
Data last refreshed: (UniProt release unknown)
Key facts
Protein FAM43B (FAM43B) is a protein from Homo sapiens identified by UniProt accession Q6ZT52, 329 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q6ZT52; gene symbol FAM43B.
- Organism: Homo sapiens.
- Length: 329 amino acids.
- Top disease associations (Open Targets): intelligence, self reported educational attainment and mathematical ability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein FAM43B |
|---|---|
| UniProt accession | Q6ZT52 |
| Gene | FAM43B |
| Organism | Homo sapiens |
| Length | 329 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- intelligence · score 0.29
- self reported educational attainment · score 0.22
- mathematical ability · score 0.07
- protein measurement · score 0.06
- verbal-numerical reasoning measurement · score 0.05
- hemoglobin measurement · score 0.03
- hepatocellular carcinoma · score 0.03
- hematocrit · score 0.02
- type 2 diabetes mellitus · score 0.02
- cognitive function measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZT52-F1 | alphafold | PREDICTED | 69.58 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZT52.
Amino-acid sequence (329 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM43B?
The strongest Open Targets associations for FAM43B are intelligence, self reported educational attainment, mathematical ability, protein measurement and verbal-numerical reasoning measurement.
How long is the FAM43B protein?
The Homo sapiens FAM43B protein (UniProt Q6ZT52) is 329 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZT52 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZT52 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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