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Solute carrier family 25 member 48 (SLC25A48)

Homo sapiens — UniProt Q6ZT89

Gene: SLC25A48Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Solute carrier family 25 member 48 (SLC25A48) is a protein from Homo sapiens identified by UniProt accession Q6ZT89, 311 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.

  • UniProt accession: Q6ZT89; gene symbol SLC25A48.
  • Organism: Homo sapiens.
  • Length: 311 amino acids.
  • Top disease associations (Open Targets): neoplasm, poisoning and eosinophil count.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameSolute carrier family 25 member 48
UniProt accessionQ6ZT89
GeneSLC25A48
OrganismHomo sapiens
Length311 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (15)

Diseases linked to this target (Open Targets).

  • neoplasm · score 0.15
  • poisoning · score 0.14
  • eosinophil count · score 0.06
  • sphingomyelin measurement · score 0.04
  • non-small cell lung carcinoma · score 0.03
  • eosinophil percentage of leukocytes · score 0.03
  • clear cell renal carcinoma · score 0.02
  • papillary thyroid carcinoma · score 0.01
  • astrocytoma · score 0.01
  • cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6ZT89-F1alphafoldPREDICTED75.48—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZT89.

Amino-acid sequence (311 residues)

MGSFQLEDFA AGWIGGAASV IVGHPLDTVK TRLQAGVGYG NTLSCIRVVY RRESMFGFFK GMSFPLASIA VYNSVVFGVF SNTQRFLSQH RCGEPEASPP RTLSDLLLAS MVAGVVSVGL GGPVDLIKIR LQMQTQPFRD ANLGLKSRAV APAEQPAYQG PVHCITTIVR NEGLAGLYRG ASAMLLRDVP GYCLYFIPYV FLSEWITPEA CTGPSPCAVW LAGGMAGAIS WGTATPMDVV KSRLQADGVY LNKYKGVLDC ISQSYQKEGL KVFFRGITVN AVRGFPMSAA MFLGYELSLQ AIRGDHAVTS P

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SLC25A48?

The strongest Open Targets associations for SLC25A48 are neoplasm, poisoning, eosinophil count, sphingomyelin measurement and non-small cell lung carcinoma.

How long is the SLC25A48 protein?

The Homo sapiens SLC25A48 protein (UniProt Q6ZT89) is 311 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6ZT89
GeneSLC25A48
OrganismHomo sapiens
Length311
Binders0
Diseases15
View on UniProt