Tubulin polyglutamylase TTLL7 (TTLL7)
Homo sapiens — UniProt Q6ZT98
Data last refreshed: (UniProt release unknown)
Key facts
Tubulin polyglutamylase TTLL7 (TTLL7) is a protein from Homo sapiens identified by UniProt accession Q6ZT98, 887 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.
- UniProt accession: Q6ZT98; gene symbol TTLL7.
- Organism: Homo sapiens.
- Length: 887 amino acids.
- Top disease associations (Open Targets): body mass index, body fat percentage and intelligence.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tubulin polyglutamylase TTLL7 |
|---|---|
| UniProt accession | Q6ZT98 |
| Gene | TTLL7 |
| Organism | Homo sapiens |
| Length | 887 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (43)
Diseases linked to this target (Open Targets).
- body mass index · score 0.38
- body fat percentage · score 0.35
- intelligence · score 0.32
- cognitive function measurement · score 0.32
- health study participation · score 0.31
- body height · score 0.28
- fat body mass · score 0.27
- schizophrenia · score 0.26
- PHF-tau measurement · score 0.25
- lean body mass · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZT98-F1 | alphafold | PREDICTED | 71.80 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZT98.
Amino-acid sequence (887 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TTLL7?
The strongest Open Targets associations for TTLL7 are body mass index, body fat percentage, intelligence, cognitive function measurement and health study participation.
How long is the TTLL7 protein?
The Homo sapiens TTLL7 protein (UniProt Q6ZT98) is 887 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZT98 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZT98 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.