About Tripartite motif-containing protein 67
Tripartite motif-containing protein 67 (TRIM67) is a protein
from Homo sapiens identified by UniProt accession
Q6ZTA4, 783 residues long.
MolForge cross-references it against 0 known binders and
72 disease associations.
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
Disease associations (72)
Diseases linked to this target (Open Targets).
- triglyceride measurement · score 0.26
- non-small cell lung carcinoma · score 0.08
- neoplasm · score 0.08
- Cerebral ischemia · score 0.08
- neck injury · score 0.07
- Obesity · score 0.07
- non-alcoholic fatty liver disease · score 0.05
- Basal ganglia calcification · score 0.04
- bilateral striopallidodentate calcinosis · score 0.04
- CACH syndrome · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
Experimental structures are not indexed in MolForge yet —
search RCSB PDB for Q6ZTA4.
Amino-acid sequence (783 residues)
MEEELKCPVC GSLFREPIIL PCSHNVCLPC ARTIAVQTPD GEQHLPQPLL LSRGSGLQAG AAAAASLEHD AAAGPACGGA GGSAAGGLGG GAGGGGDHAD KLSLYSETDS GYGSYTPSLK SPNGVRVLPM VPAPPGSSAA AARGAACSSL SSSSSSITCP QCHRSASLDH RGLRGFQRNR LLEAIVQRYQ QGRGAVPGTS AAAAVAICQL CDRTPPEPAA TLCEQCDVLY CSACQLKCHP SRGPFAKHRL VQPPPPPPPP AEAASGPTGT AQGAPSGGGG CKSPGGAGAG ATGGSTARKF PTCPEHEMEN YSMYCVSCRT PVCYLCLEEG RHAKHEVKPL GAMWKQHKAQ LSQALNGVSD KAKEAKEFLV QLKNILQQIQ ENGLDYEACL VAQCDALVDA LTRQKAKLLT KVTKEREHKL KMVWDQINHC TLKLRQSTGL MEYCLEVIKE NDPSGFLQIS DALIKRVQVS QEQWVKGALE PKVSAEFDLT LDSEPLLQAI HQLDFIQMKC RVPPVPLLQL EKCCTRNNSV TLAWRMPPFT HSPVDGYILE LDDGAGGQFR EVYVGKETLC TIDGLHFNST YNARVKAFNS SGVGPYSKTV VLQTSDVAWF TFDPNSGHRD IILSNDNQTA TCSSYDDRVV LGTAAFSKGV HYWELHVDRY DNHPDPAFGV ARASVVKDMM LGKDDKAWAM YVDNNRSWFM HCNSHTNRTE GGVCKGATVG VLLDLNKHTL TFFINGQQQG PTAFSHVDGV FMPALSLNRN VQVTLHTGLE VPTNLGRPKL SGN
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