Refilin-A (RFLNA)
Homo sapiens — UniProt Q6ZTI6
Data last refreshed: (UniProt release unknown)
Key facts
Refilin-A (RFLNA) is a protein from Homo sapiens identified by UniProt accession Q6ZTI6, 216 residues long. MolForge cross-references it against 0 known binders and 99 disease associations.
- UniProt accession: Q6ZTI6; gene symbol RFLNA.
- Organism: Homo sapiens.
- Length: 216 amino acids.
- Top disease associations (Open Targets): BMI-adjusted waist-hip ratio, triglyceride measurement and high density lipoprotein cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Refilin-A |
|---|---|
| UniProt accession | Q6ZTI6 |
| Gene | RFLNA |
| Organism | Homo sapiens |
| Length | 216 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (99)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist-hip ratio · score 0.48
- triglyceride measurement · score 0.48
- high density lipoprotein cholesterol measurement · score 0.48
- heel bone mineral density · score 0.44
- body fat percentage · score 0.44
- sex hormone-binding globulin measurement · score 0.43
- BMI-adjusted hip circumference · score 0.43
- waist-hip ratio · score 0.43
- body height · score 0.42
- reticulocyte count · score 0.42
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZTI6-F1 | alphafold | PREDICTED | 58.71 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZTI6.
Amino-acid sequence (216 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RFLNA?
The strongest Open Targets associations for RFLNA are BMI-adjusted waist-hip ratio, triglyceride measurement, high density lipoprotein cholesterol measurement, heel bone mineral density and body fat percentage.
How long is the RFLNA protein?
The Homo sapiens RFLNA protein (UniProt Q6ZTI6) is 216 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZTI6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZTI6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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