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Ras association domain-containing protein 6 (RASSF6)

Homo sapiens — UniProt Q6ZTQ3

Gene: RASSF6Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Ras association domain-containing protein 6 (RASSF6) is a protein from Homo sapiens identified by UniProt accession Q6ZTQ3, 369 residues long. MolForge cross-references it against 0 known binders and 75 disease associations.

  • UniProt accession: Q6ZTQ3; gene symbol RASSF6.
  • Organism: Homo sapiens.
  • Length: 369 amino acids.
  • Top disease associations (Open Targets): prostate carcinoma, serum urea measurement and cystatin C measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameRas association domain-containing protein 6
UniProt accessionQ6ZTQ3
GeneRASSF6
OrganismHomo sapiens
Length369 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (75)

Diseases linked to this target (Open Targets).

  • prostate carcinoma · score 0.48
  • serum urea measurement · score 0.34
  • cystatin C measurement · score 0.34
  • hair color · score 0.33
  • hair colour measurement · score 0.33
  • creatinine measurement · score 0.32
  • urate measurement · score 0.29
  • C-X-C motif chemokine 6 measurement · score 0.28
  • afamin measurement · score 0.26
  • Disorder of lipid metabolism · score 0.22

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6ZTQ3-F1alphafoldPREDICTED70.08—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZTQ3.

Amino-acid sequence (369 residues)

MLWEETGAAP APARASDLPY RISSDHLKKE EKMTMMAHQY PSWIFINEKT FITREQLNSL LKTYNIFYEN QKNLHILYGE TEDGKLIVEG MLDIFWGVKR PIQLKIQDEK PFSSFTSMKS SDVFSSKGMT RWGEFDDLYR ISELDRTQIP MSEKRNSQED YLSYHSNTLK PHAKDEPDSP VLYRTMSEAA LVRKRMKPLM MDRKERQKNR ASINGHFYNH ETSIFIPAFE SETKVRVNSN MRTEEVIKQL LQKFKIENSP QDFALHIIFA TGEQRRLKKT DIPLLQRLLQ GPSEKNARIF LMDKDAEEIS SDVAQYINFH FSLLESILQR LNEEEKREIQ RIVTKFNKEK AIILKCLQNK LVIKTETTV

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with RASSF6?

The strongest Open Targets associations for RASSF6 are prostate carcinoma, serum urea measurement, cystatin C measurement, hair color and hair colour measurement.

How long is the RASSF6 protein?

The Homo sapiens RASSF6 protein (UniProt Q6ZTQ3) is 369 amino acids long.

Browse: Targets: R · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6ZTQ3
GeneRASSF6
OrganismHomo sapiens
Length369
Binders0
Diseases75
View on UniProt