Cadherin-related family member 3 (CDHR3)
Homo sapiens — UniProt Q6ZTQ4
Data last refreshed: (UniProt release unknown)
Key facts
Cadherin-related family member 3 (CDHR3) is a protein from Homo sapiens identified by UniProt accession Q6ZTQ4, 885 residues long. MolForge cross-references it against 0 known binders and 100 disease associations.
- UniProt accession: Q6ZTQ4; gene symbol CDHR3.
- Organism: Homo sapiens.
- Length: 885 amino acids.
- Top disease associations (Open Targets): bone quantitative ultrasound measurement, susceptibility to childhood ear infection measurement and Abnormal mastoid morphology.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cadherin-related family member 3 |
|---|---|
| UniProt accession | Q6ZTQ4 |
| Gene | CDHR3 |
| Organism | Homo sapiens |
| Length | 885 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (100)
Diseases linked to this target (Open Targets).
- bone quantitative ultrasound measurement · score 0.34
- susceptibility to childhood ear infection measurement · score 0.31
- Abnormal mastoid morphology · score 0.30
- childhood onset asthma · score 0.25
- C-reactive protein measurement · score 0.25
- asthma exacerbation measurement · score 0.25
- middle ear disorder · score 0.24
- non-suppurative otitis media · score 0.24
- disorder of ear · score 0.23
- asthma · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZTQ4-F1 | alphafold | PREDICTED | 77.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZTQ4.
Amino-acid sequence (885 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CDHR3?
The strongest Open Targets associations for CDHR3 are bone quantitative ultrasound measurement, susceptibility to childhood ear infection measurement, Abnormal mastoid morphology, childhood onset asthma and C-reactive protein measurement.
How long is the CDHR3 protein?
The Homo sapiens CDHR3 protein (UniProt Q6ZTQ4) is 885 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZTQ4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZTQ4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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