Septin-14 (SEPTIN14)
Homo sapiens — UniProt Q6ZU15
Data last refreshed: (UniProt release unknown)
Key facts
Septin-14 (SEPTIN14) is a protein from Homo sapiens identified by UniProt accession Q6ZU15, 432 residues long. MolForge cross-references it against 0 known binders and 57 disease associations.
- UniProt accession: Q6ZU15; gene symbol SEPTIN14.
- Organism: Homo sapiens.
- Length: 432 amino acids.
- Top disease associations (Open Targets): appendicular lean mass, body height and serum alanine aminotransferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Septin-14 |
|---|---|
| UniProt accession | Q6ZU15 |
| Gene | SEPTIN14 |
| Organism | Homo sapiens |
| Length | 432 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (57)
Diseases linked to this target (Open Targets).
- appendicular lean mass · score 0.39
- body height · score 0.31
- serum alanine aminotransferase measurement · score 0.27
- lean body mass · score 0.25
- fat body mass · score 0.25
- whole body water mass · score 0.24
- IGF-1 measurement · score 0.23
- type 2 diabetes mellitus · score 0.10
- lymphocyte percentage of leukocytes · score 0.05
- hemolytic anemia due to glutathione reductase deficiency · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZU15-F1 | alphafold | PREDICTED | 81.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZU15.
Amino-acid sequence (432 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SEPTIN14?
The strongest Open Targets associations for SEPTIN14 are appendicular lean mass, body height, serum alanine aminotransferase measurement, lean body mass and fat body mass.
How long is the SEPTIN14 protein?
The Homo sapiens SEPTIN14 protein (UniProt Q6ZU15) is 432 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZU15 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZU15 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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