Putative C-type lectin domain family 20 member A (CLEC20A)
Homo sapiens — UniProt Q6ZU45
Data last refreshed: (UniProt release unknown)
Key facts
Putative C-type lectin domain family 20 member A (CLEC20A) is a protein from Homo sapiens identified by UniProt accession Q6ZU45, 400 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q6ZU45; gene symbol CLEC20A.
- Organism: Homo sapiens.
- Length: 400 amino acids.
- Top disease associations (Open Targets): serum gamma-glutamyl transferase measurement, high density lipoprotein cholesterol measurement and Red cell distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Putative C-type lectin domain family 20 member A |
|---|---|
| UniProt accession | Q6ZU45 |
| Gene | CLEC20A |
| Organism | Homo sapiens |
| Length | 400 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- serum gamma-glutamyl transferase measurement · score 0.10
- high density lipoprotein cholesterol measurement · score 0.08
- Red cell distribution width · score 0.07
- low density lipoprotein cholesterol measurement · score 0.05
- total blood protein measurement · score 0.05
- calcium measurement · score 0.05
- apolipoprotein A 1 measurement · score 0.05
- serum albumin measurement · score 0.05
- mean corpuscular hemoglobin concentration · score 0.05
- alcohol consumption measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZU45-F1 | alphafold | PREDICTED | 71.55 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZU45.
Amino-acid sequence (400 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CLEC20A?
The strongest Open Targets associations for CLEC20A are serum gamma-glutamyl transferase measurement, high density lipoprotein cholesterol measurement, Red cell distribution width, low density lipoprotein cholesterol measurement and total blood protein measurement.
How long is the CLEC20A protein?
The Homo sapiens CLEC20A protein (UniProt Q6ZU45) is 400 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZU45 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZU45 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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