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Uncharacterized protein KIAA0408 (KIAA0408)

Homo sapiens — UniProt Q6ZU52

Gene: KIAA0408Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Uncharacterized protein KIAA0408 (KIAA0408) is a protein from Homo sapiens identified by UniProt accession Q6ZU52, 694 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.

  • UniProt accession: Q6ZU52; gene symbol KIAA0408.
  • Organism: Homo sapiens.
  • Length: 694 amino acids.
  • Top disease associations (Open Targets): waist-hip ratio, heel bone mineral density and self reported educational attainment.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameUncharacterized protein KIAA0408
UniProt accessionQ6ZU52
GeneKIAA0408
OrganismHomo sapiens
Length694 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (14)

Diseases linked to this target (Open Targets).

  • waist-hip ratio · score 0.36
  • heel bone mineral density · score 0.36
  • self reported educational attainment · score 0.29
  • mathematical ability · score 0.20
  • bone quantitative ultrasound measurement · score 0.10
  • breast disease · score 0.03
  • body height · score 0.02
  • body fat percentage · score 0.02
  • colorectal cancer · score 0.01
  • papillary thyroid carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6ZU52-F1alphafoldPREDICTED51.69—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZU52.

Amino-acid sequence (694 residues)

MDLHKQWENT ETNWHKEKME LLDQFDNERK EWESQWKIMQ KKIEELCREV KLWRKININE SAKIIDLYHE KTIPEKVIES SPNYPDLGQS EFIRTNHKDG LRKENKREQS LVSGGNQMCK EQKATKKSKV GFLDPLATDN QKECEAWPDL RTSEEDSKSC SGALSTALEE LAKVSEELCS FQEEIRKRSN HRRMKSDSFL QEMPNVTNIP HGDPMINNDQ CILPISLEKE KQKNRKNLSC TNVLQSNSTK KCGIDTIDLK RNETPPVPPP RSTSRNFPSS DSEQAYERWK ERLDHNSWVP HEGRSKRNYN PHFPLRQQEM SMLYPNEGKT SKDGIIFSSL VPEVKIDSKP PSNEDVGLSM WSCDIGIGAK RSPSTSWFQK TCSTPSNPKY EMVIPDHPAK SHPDLHVSND CSSSVAESSS PLRNFSCGFE RTTRNEKLAA KTDEFNRTVF RTDRNCQAIQ QNHSCSKSSE DLKPCDTSST HTGSISQSND VSGIWKTNAH MPVPMENVPD NPTKKSTTGL VRQMQGHLSP RSYRNMLHEH DWRPSNLSGR PRSADPRSNY GVVEKLLKTY ETATESALQN SKCFQDNWTK CNSDVSGGAT LSQHLEMLQM EQQFQQKTAV WGGQEVKQGI DPKKITEESM SVNASHGKGF SRPARPANRR LPSRWASRSP SAPPALRRTT HNYTISLRSE ALMV

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with KIAA0408?

The strongest Open Targets associations for KIAA0408 are waist-hip ratio, heel bone mineral density, self reported educational attainment, mathematical ability and bone quantitative ultrasound measurement.

How long is the KIAA0408 protein?

The Homo sapiens KIAA0408 protein (UniProt Q6ZU52) is 694 amino acids long.

Browse: Targets: K · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6ZU52
GeneKIAA0408
OrganismHomo sapiens
Length694
Binders0
Diseases14
View on UniProt