BEN domain-containing protein 4 (BEND4)
Homo sapiens — UniProt Q6ZU67
Data last refreshed: (UniProt release unknown)
Key facts
BEN domain-containing protein 4 (BEND4) is a protein from Homo sapiens identified by UniProt accession Q6ZU67, 534 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q6ZU67; gene symbol BEND4.
- Organism: Homo sapiens.
- Length: 534 amino acids.
- Top disease associations (Open Targets): alcohol consumption measurement, unipolar depression and neuroticism measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | BEN domain-containing protein 4 |
|---|---|
| UniProt accession | Q6ZU67 |
| Gene | BEND4 |
| Organism | Homo sapiens |
| Length | 534 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- alcohol consumption measurement · score 0.47
- unipolar depression · score 0.37
- neuroticism measurement · score 0.35
- autism spectrum disorder · score 0.29
- adolescent idiopathic scoliosis · score 0.26
- neurodegenerative disease · score 0.26
- depressive symptom measurement · score 0.25
- Abnormality of refraction · score 0.24
- arterial stiffness measurement · score 0.17
- genetic disorder · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZU67-F1 | alphafold | PREDICTED | 59.12 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZU67.
Amino-acid sequence (534 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BEND4?
The strongest Open Targets associations for BEND4 are alcohol consumption measurement, unipolar depression, neuroticism measurement, autism spectrum disorder and adolescent idiopathic scoliosis.
How long is the BEND4 protein?
The Homo sapiens BEND4 protein (UniProt Q6ZU67) is 534 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZU67 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZU67 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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