Transmembrane protein 26 (TMEM26)
Homo sapiens — UniProt Q6ZUK4
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 26 (TMEM26) is a protein from Homo sapiens identified by UniProt accession Q6ZUK4, 368 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.
- UniProt accession: Q6ZUK4; gene symbol TMEM26.
- Organism: Homo sapiens.
- Length: 368 amino acids.
- Top disease associations (Open Targets): diet measurement, PR interval and intraocular pressure measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 26 |
|---|---|
| UniProt accession | Q6ZUK4 |
| Gene | TMEM26 |
| Organism | Homo sapiens |
| Length | 368 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (45)
Diseases linked to this target (Open Targets).
- diet measurement · score 0.34
- PR interval · score 0.34
- intraocular pressure measurement · score 0.33
- PHF-tau measurement · score 0.33
- body mass index · score 0.32
- neurodegenerative disease · score 0.30
- self reported educational attainment · score 0.28
- age at first sexual intercourse measurement · score 0.25
- C-reactive protein measurement · score 0.24
- body height · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZUK4-F1 | alphafold | PREDICTED | 77.54 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZUK4.
Amino-acid sequence (368 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM26?
The strongest Open Targets associations for TMEM26 are diet measurement, PR interval, intraocular pressure measurement, PHF-tau measurement and body mass index.
How long is the TMEM26 protein?
The Homo sapiens TMEM26 protein (UniProt Q6ZUK4) is 368 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZUK4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZUK4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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