FOXL2 neighbor protein (FOXL2NB)
Homo sapiens — UniProt Q6ZUU3
Data last refreshed: (UniProt release unknown)
Key facts
FOXL2 neighbor protein (FOXL2NB) is a protein from Homo sapiens identified by UniProt accession Q6ZUU3, 175 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q6ZUU3; gene symbol FOXL2NB.
- Organism: Homo sapiens.
- Length: 175 amino acids.
- Top disease associations (Open Targets): facial hair thickness measurement, platelet count and cortical surface area measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | FOXL2 neighbor protein |
|---|---|
| UniProt accession | Q6ZUU3 |
| Gene | FOXL2NB |
| Organism | Homo sapiens |
| Length | 175 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- facial hair thickness measurement · score 0.28
- platelet count · score 0.23
- cortical surface area measurement · score 0.20
- brain measurement · score 0.20
- cortical thickness · score 0.20
- neuroimaging measurement · score 0.16
- hair shape measurement · score 0.06
- 3-hydroxypropylmercapturic acid measurement · score 0.06
- non-small cell lung carcinoma · score 0.03
- endometrial carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZUU3-F1 | alphafold | PREDICTED | 48.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZUU3.
Amino-acid sequence (175 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FOXL2NB?
The strongest Open Targets associations for FOXL2NB are facial hair thickness measurement, platelet count, cortical surface area measurement, brain measurement and cortical thickness.
How long is the FOXL2NB protein?
The Homo sapiens FOXL2NB protein (UniProt Q6ZUU3) is 175 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZUU3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZUU3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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