Patatin-like phospholipase domain-containing protein 7 (PNPLA7)
Homo sapiens — UniProt Q6ZV29
Data last refreshed: (UniProt release unknown)
Key facts
Patatin-like phospholipase domain-containing protein 7 (PNPLA7) is a protein from Homo sapiens identified by UniProt accession Q6ZV29, 1317 residues long. MolForge cross-references it against 0 known binders and 51 disease associations.
- UniProt accession: Q6ZV29; gene symbol PNPLA7.
- Organism: Homo sapiens.
- Length: 1317 amino acids.
- Top disease associations (Open Targets): calcium measurement, creatinine measurement and glioblastoma multiforme.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Patatin-like phospholipase domain-containing protein 7 |
|---|---|
| UniProt accession | Q6ZV29 |
| Gene | PNPLA7 |
| Organism | Homo sapiens |
| Length | 1317 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (51)
Diseases linked to this target (Open Targets).
- calcium measurement · score 0.26
- creatinine measurement · score 0.24
- glioblastoma multiforme · score 0.23
- breast adenocarcinoma · score 0.23
- primary ovarian insufficiency · score 0.12
- peripheral neuropathy, autosomal recessive, with or without impaired intellectual development · score 0.12
- head and neck squamous cell carcinoma · score 0.11
- mulibrey nanism · score 0.11
- body mass index · score 0.07
- obesity due to melanocortin 4 receptor deficiency · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZV29-F1 | alphafold | PREDICTED | 71.21 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZV29.
Amino-acid sequence (1317 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PNPLA7?
The strongest Open Targets associations for PNPLA7 are calcium measurement, creatinine measurement, glioblastoma multiforme, breast adenocarcinoma and primary ovarian insufficiency.
How long is the PNPLA7 protein?
The Homo sapiens PNPLA7 protein (UniProt Q6ZV29) is 1317 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZV29 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZV29 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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