Protein FAM47E (FAM47E)
Homo sapiens — UniProt Q6ZV65
Data last refreshed: (UniProt release unknown)
Key facts
Protein FAM47E (FAM47E) is a protein from Homo sapiens identified by UniProt accession Q6ZV65, 393 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: Q6ZV65; gene symbol FAM47E.
- Organism: Homo sapiens.
- Length: 393 amino acids.
- Top disease associations (Open Targets): sex hormone-binding globulin measurement, Parkinson disease and alkaline phosphatase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein FAM47E |
|---|---|
| UniProt accession | Q6ZV65 |
| Gene | FAM47E |
| Organism | Homo sapiens |
| Length | 393 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- sex hormone-binding globulin measurement · score 0.37
- Parkinson disease · score 0.29
- alkaline phosphatase measurement · score 0.25
- platelet count · score 0.25
- testosterone measurement · score 0.24
- hemoglobin measurement · score 0.23
- high density lipoprotein cholesterol measurement · score 0.21
- sleep duration · score 0.21
- mean corpuscular hemoglobin concentration · score 0.21
- mean corpuscular volume · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZV65-F1 | alphafold | PREDICTED | 61.75 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZV65.
Amino-acid sequence (393 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM47E?
The strongest Open Targets associations for FAM47E are sex hormone-binding globulin measurement, Parkinson disease, alkaline phosphatase measurement, platelet count and testosterone measurement.
How long is the FAM47E protein?
The Homo sapiens FAM47E protein (UniProt Q6ZV65) is 393 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZV65 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZV65 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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