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LanC-like protein 3 (LANCL3)

Homo sapiens — UniProt Q6ZV70

Gene: LANCL3Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

LanC-like protein 3 (LANCL3) is a protein from Homo sapiens identified by UniProt accession Q6ZV70, 420 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.

  • UniProt accession: Q6ZV70; gene symbol LANCL3.
  • Organism: Homo sapiens.
  • Length: 420 amino acids.
  • Top disease associations (Open Targets): autosomal recessive hypophosphatemic rickets, melorheostosis and Osteoporosis.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameLanC-like protein 3
UniProt accessionQ6ZV70
GeneLANCL3
OrganismHomo sapiens
Length420 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (14)

Diseases linked to this target (Open Targets).

  • autosomal recessive hypophosphatemic rickets · score 0.04
  • melorheostosis · score 0.04
  • Osteoporosis · score 0.04
  • osteoporosis · score 0.04
  • pyknoachondrogenesis · score 0.03
  • medulloblastoma · score 0.01
  • Leishmaniasis · score 0.01
  • Crohn's disease · score 0.01
  • primitive neuroectodermal tumor · score 0.00
  • cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6ZV70-F1alphafoldPREDICTED93.00—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZV70.

Amino-acid sequence (420 residues)

MDTKRCFANR FDDYQGSLLA GQCEEAVAPL VTATIERILQ ELPPLGGGAE ARGATAGASA CQGGLYGGVA GVAYMLYHVS QSPLFATARE RYLRSAKRLI DACARAEEWG EPDADTRAAF LLGGAGVYAV ATLVYHALGR SDYVQPLGKF RALCAVCAPV SFLECGSDEL FVGRAGYLCA ALVLKQKLAQ EVLTPAQIKS ICQAILDSGK QYAIKKRKPF PLMYSYYGTE YLGAAHGLSS ILQMLLSYHE HLKPSDRELV WQSVDFLMEQ EQNCNWPPEL GETIERENEL VHWCHGAPGI AYLFAKAYLV SKKPQYLDTC IRCGELTWQK GLLKKGPGIC HGVAGSAYVF LLLYRLTGNS KYIYRAQRFA QFLFTEEFKA GSRVLESIYS LYEGFSGTVC FLIDLLQPNQ AEFPLFSVFV

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with LANCL3?

The strongest Open Targets associations for LANCL3 are autosomal recessive hypophosphatemic rickets, melorheostosis, Osteoporosis, osteoporosis and pyknoachondrogenesis.

How long is the LANCL3 protein?

The Homo sapiens LANCL3 protein (UniProt Q6ZV70) is 420 amino acids long.

Browse: Targets: L · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6ZV70
GeneLANCL3
OrganismHomo sapiens
Length420
Binders0
Diseases14
View on UniProt