G protein-regulated inducer of neurite outgrowth 3 (GPRIN3)
Homo sapiens — UniProt Q6ZVF9
Data last refreshed: (UniProt release unknown)
Key facts
G protein-regulated inducer of neurite outgrowth 3 (GPRIN3) is a protein from Homo sapiens identified by UniProt accession Q6ZVF9, 776 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.
- UniProt accession: Q6ZVF9; gene symbol GPRIN3.
- Organism: Homo sapiens.
- Length: 776 amino acids.
- Top disease associations (Open Targets): lymphocyte count, body height and monocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | G protein-regulated inducer of neurite outgrowth 3 |
|---|---|
| UniProt accession | Q6ZVF9 |
| Gene | GPRIN3 |
| Organism | Homo sapiens |
| Length | 776 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (39)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.49
- body height · score 0.34
- monocyte count · score 0.33
- myeloid white cell count · score 0.32
- leukocyte count · score 0.31
- DNA methylation · score 0.30
- neurodegenerative disease · score 0.28
- lymphocyte percentage of leukocytes · score 0.28
- Acute kidney injury · score 0.05
- mean platelet volume · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZVF9-F1 | alphafold | PREDICTED | 46.89 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZVF9.
Amino-acid sequence (776 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GPRIN3?
The strongest Open Targets associations for GPRIN3 are lymphocyte count, body height, monocyte count, myeloid white cell count and leukocyte count.
How long is the GPRIN3 protein?
The Homo sapiens GPRIN3 protein (UniProt Q6ZVF9) is 776 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZVF9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZVF9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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