Transmembrane protein 179 (TMEM179)
Homo sapiens — UniProt Q6ZVK1
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 179 (TMEM179) is a protein from Homo sapiens identified by UniProt accession Q6ZVK1, 233 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q6ZVK1; gene symbol TMEM179.
- Organism: Homo sapiens.
- Length: 233 amino acids.
- Top disease associations (Open Targets): rheumatoid arthritis, acalculous cholecystitis and brain volume measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 179 |
|---|---|
| UniProt accession | Q6ZVK1 |
| Gene | TMEM179 |
| Organism | Homo sapiens |
| Length | 233 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- rheumatoid arthritis · score 0.30
- acalculous cholecystitis · score 0.29
- brain volume measurement · score 0.29
- platelet count · score 0.09
- platelet crit · score 0.07
- blood protein measurement · score 0.05
- COVID-19 · score 0.02
- breast carcinoma · score 0.02
- non-small cell lung carcinoma · score 0.01
- uterine leiomyosarcoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZVK1-F1 | alphafold | PREDICTED | 89.01 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZVK1.
Amino-acid sequence (233 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM179?
The strongest Open Targets associations for TMEM179 are rheumatoid arthritis, acalculous cholecystitis, brain volume measurement, platelet count and platelet crit.
How long is the TMEM179 protein?
The Homo sapiens TMEM179 protein (UniProt Q6ZVK1) is 233 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZVK1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZVK1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.